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Trends in pancreatic cancer mortality in Europe in the years 1995-2018
Opltová, Michaela ; Kulhánová, Ivana (advisor) ; Altová, Anna (referee)
Trends in pancreatic cancer mortality in Europe in the years 1995-2018 Abstract Malignant neoplasm of the pancreas is one of the malignant diseases with the worst survival statistics. The death rate per year is currently almost equal to the incidence rate in the world. Europe, along with other developed regions, is among the most affected areas. The aim of this bachelor's thesis is to analyse the development of the intensity of mortality due to malignant neoplasm of the pancreas in selected European countries between 1995 and 2018 and the subsequent comparison of trends between countries and within individual regions. Standardized mortality rates and age-specific mortality rates were mainly used for this purpose. Data came from the WHO Mortality Database and the Human Mortality Database. All states experienced an increase in standardized mortality rates for pancreatic cancer in both sexes. The states of Central and Northern Europe recorded higher values for both sexes, while the lowest values were recorded by the states of Southern Europe. Specific mortality rates increased with age in both sexes also in all analysed states. Key words: mortality, malignant neoplasm of the pancreas, Europe, standardized mortality rate
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Age-specific analysis of leukemia incidence and mortality
Soukupová, Alžběta ; Kulhánová, Ivana (advisor) ; Altová, Anna (referee)
The purpose of this bachelor's thesis is to analyze the trends in incidence and mortality from leukemia in Czechia with special focus on the trends by gender and age. The analysis of the incidence of leukemia was conducted between 1980 and 2018 and the analysis of mortality in the period between 2003 to 2020. The period for mortality had to be shortened due to the availability of the necessary data. For both analyses, standardized rates were calculated. Due to the low number of deaths, the standardized death rates were divided into larger age groups and combined into six-year periods. Based on the results, it was found that the incidence of leukemia is increasing in Czechia. The number of new cases of disease and death increases with age and is higher in men than in women. The trends in mortality in women is more stable than in men. Acute forms of leukemia dominate in childhood and cases of chronic leukemia begin to appear with age. In senior age, both types are represented equally. The largest number of people die each year from the acute myeloid leukemia (AML) and the least from the acute lymphoblastic leukemia (ALL). In the chronic types of this disease, such as chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML), there are frequent fluctuations over time and their development...
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Sex-specific analysis of mortality for malignant neoplasms in the Czech Republic in the years 1994-2013
Maláková, Kateřina ; Hulíková Tesárková, Klára (advisor) ; Kohoutová, Barbora (referee)
Sex-specific analysis of mortality for malignant neoplasms in the Czech Republic in the years 1994-2013 Abstract The aim of this bachelor thesis is to analyze and describe the evolution of mortality due to malignant neoplasms in the Czech Republic from 1994 to 2013 and to study mortality of malignant neoplasms by sexes in detail in the chosen spatial and temporal distribution for the purpose of identifying possible factors which can have an influence on differences between men and women. This thesis deals with mortality from selected causes of death in the malignant neoplasms in addition to the analysis of mortality for the whole group of malignant tumours. There was used standardized mortality rate as the main indicator of mortality and the probability of death by age and decomposition of the difference in life expectancy at birth by cause of death and age between 1994 and 2013 were also used as a more detailed analysis of mortality. During the reported period standardized mortality rate decreased for the whole group of malignant neoplasms and for most particular causes of death for both sexes. It was also found that the differences between men and women are rather decreasing, but for some causes of death such as malignant neoplasm of colon, malignant neoplasm of bronchus and lungs, and malignant neoplasm...
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